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REVIEW ARTICLE
Year : 2007  |  Volume : 4  |  Issue : 1  |  Page : 107-117

Management of severe acute hepatitis B


Department of Gastroenterology and Metabolic Disorders, Pushpawati Singhania Research Institute for Liver, Renal and Digestive Diseases, Sheikh Sarai, Phase II, Press Enclave Road, New Delhi-110 017, India

Correspondence Address:
Sudeep Khanna
Department of Gastroenterology and Metabolic Disorders, Pushpawati Singhania Research Institute for Liver, Renal and Digestive Diseases, Sheikh Sarai, Phase II, Press Enclave Road, New Delhi-110 017
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0972-9747.45092

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HBV infection is a major public health problem. Acute viral hepatitis B is successfully cleared in more than 95% of immunocompetent patients. HBV infection can cause severe acute hepatitis which can progress to acute liver failure. The purpose of this review is to discuss the immune response in acute hepatitis B and the possible role of HBV genotypes in development of severe acute HBV related hepatitis, define severe acute hepatitis B and to look at the role of the available antivirals in this clinical setting.


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