author = {Khanna, Sudeep. and Tandon, Rakesh.}, title = {{Management of severe acute hepatitis B}}, journal ={Hepatitis B Annual}, volume ={4}, number ={1}, pages = {107-117}, doi = {10.4103/0972-9747.45092}, year = {2007}, abstract ={HBV infection is a major public health problem. Acute viral hepatitis B is successfully cleared in more than 95% of immunocompetent patients. HBV infection can cause severe acute hepatitis which can progress to acute liver failure. The purpose of this review is to discuss the immune response in acute hepatitis B and the possible role of HBV genotypes in development of severe acute HBV related hepatitis, define severe acute hepatitis B and to look at the role of the available antivirals in this clinical setting.}, URL ={https://www.hepatitisbannual.org/article.asp?issn=0972-9747;year=2007;volume=4;issue=1;spage=107;epage=117;aulast=Khanna;t=6}, eprint ={https://www.hepatitisbannual.org/article.asp?issn=0972-9747;year=2007;volume=4;issue=1;spage=107;epage=117;aulast=Khanna;t=6} }